Total synthesis of (+)-bretonin B: access to the (E,Z,E)-triene core by a late-stage Peterson elimination of a convergently assembled silyl ether.
نویسندگان
چکیده
The title compound was synthesised in a concise route (nine linear steps, 31% overall yield) employing an α-silyl epoxide ring opening, a Julia-Kocienski olefination and a late-stage Peterson elimination as key steps.
منابع مشابه
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عنوان ژورنال:
- Chemical communications
دوره 48 95 شماره
صفحات -
تاریخ انتشار 2012